White-rot fungi produce a wide range of organohalogen metabolites. The most com­monly produced halogens are chlorinated anisyl metabolites (CAM) and chlorinated hydroquinone metabolites (CHM). CAM has an important physiological function in lignin degradation, contributing as substrates forAAO involved in extracellular H2O2 production. Among CHM metabolites, chlorinated 1,4-dimethoxybenzene such as

2- chloro-1,4-dimethoxybenzene, 2,6-dichloro-1,4-dimethoxybenzene, tetrachloro-

1.4- dimethoxybenzene, and tetrachloro-4-methoxyphenol are identified. 2-Chloro-

1.4- dimethoxybenzene (2-Cl-1,4-DMB) is another substrate for LiP, indicating a possible active function in the wood decomposition process. Like VA, it can also act as a redox mediator [98, 127].