Radiochromatography

As mentioned in Section 10.1.2, traditional analytical methods can be coupled with radioactive tracer techniques, or qualitative and quantitative analysis of the labeled compounds can be performed by any traditional analytical technique. One such method is radiochromatography, which is frequently used for purification and qual­ity control of radiochemicals and radiopharmaceuticals (radiochemical purity con­trol, as discussed in Section 8.3). Any types of chromatography, namely, HPLC, thin-layer chromatography, and ion exchange chromatography, can be used for this purpose. The detection is done by measuring the radioactivity of the fractions. Radiochromatogram scanners are commercially available.