The future widespread planting of switchgrass as a bioenergy crop is a highly multidimensional and complex issue. Apart from the highly important social and economic components, which this chapter does little more than make mention of their existence, there is room for further work on a number of aspects that may strengthen the argument for its incorporation into the landscape and the fabric of near-future bioenergy portfolios. Critical pressing and future research can easily be tied to target areas discussed in this chapter. More specifically, improvements in (a) biomass and ethanol outputs, (b) other growth aspects and plant protection, and (c) multi-use possibilities, will simultaneously require recognition of environmentally sustainable outcomes (Box 1). The breeding and biotechnological programs essential to these endeavors (see Aguirre et al. 2012) will benefit from concurrent genomics efforts (e. g., Palmer et al. 2012; Wang et al. 2012).