Polyacrylamide gels are formed by polymerization of acrylamide by the action of a crosslinked agent, is chemically inert, uniform properties, able to be prepared quickly and reproducibly. Thus, in addition, transparent gels with mechanical stability, water insoluble, relatively non-ionic and allow good visualization of the bands for a long time. Also has the advantage that by varying the concentration of polymers can be modified in a controlled manner the pore size, there sometimes is used in diagnosis least because of their neurotoxocidad [59].

Whole cell immobilization within a polyacrylamide gel also provides a useful laboratory scale system and has been used to biosorb and recover a number of heavy metal(s). Good results have been obtained in the case of polyacrylamide immobilized cells of Citrobacter where a very high removal of uranium, cadmium and lead was observed from solutions supplemented with glycerol -2PO4. Rhizopus arrhizus biomass immobilized on polyacrylamide gel was effective in almost completely removing Cu2+ Co2+ and Cd2+ from synthetic metal solution [26, 55].