Poly-g-Glutamic Acid

PGA was first observed by Ivanovics et al. produced by Bacillus anthracis strain during 1937. The traditional Japanese food natto (fermented product made from soyabean) consists of PGA and a fructan, and is pro­duced through fermentation using the strain Bacillus natto. PGA produced can be essentially of three types,

a polymer purely made of either D-glutamic acid, L-glu — tamic acid, or d and L-glutamic acid. Besides Bacillus, other microbial species from Archaea (Natrialba aegyp — tiaca, Natronococcus occultus), eubacteria as well as eu­karyotes (hydra) were found to produce PGA (Kocianova et al., 2005; Hezayen et al., 2001). PGA is one of the most utilized poly(amino acid)s, with multi­tude of applications ranging from agriculture to cos­metics, food industry and even pharmaceuticals (Buescher and Margaritis, 2007).